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Found 19 results
Author
Title
Type
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Year
]
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Author
is
Wang, Chao
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2024
Bravo CParra
,
Krukowski K
,
Barker S
,
Wang C
,
Li Y
,
Fan L
,
Vázquez-Rosa E
,
Shin M-K
,
Wong MYing
,
McCullough LD
et al.
. 2024.
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
.
Mol Neurodegener. 19(1):51.
2022
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Tracy TE
,
Madero-Pérez J
,
Swaney DL
,
Chang TS
,
Moritz M
,
Konrad C
,
Ward ME
,
Stevenson E
,
Huttenhain R
,
Kauwe G
et al.
. 2022.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
.
Cell. 185(4):712-728.e14.
2021
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
2020
Chen X
,
Li Y
,
Wang C
,
Tang Y
,
Mok S-A
,
Tsai RM
,
Rojas JC
,
Karydas A
,
Miller BL
,
Boxer AL
et al.
. 2020.
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
.
Mol Neurodegener. 15(1):2.
2019
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
Song M
,
Yang X
,
Ren X
,
Maliskova L
,
Li B
,
Jones IR
,
Wang C
,
Jacob F
,
Wu K
,
Traglia M
et al.
. 2019.
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.
.
Nat Genet. 51(8):1252-1262.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
2018
Wang C
,
Telpoukhovskaia MA
,
Bahr BA
,
Chen X
,
Gan L
. 2018.
Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases.
.
Curr Opin Neurobiol. 48:52-58.
Fernandopulle MS
,
Prestil R
,
Grunseich C
,
Wang C
,
Gan L
,
Ward ME
. 2018.
Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.
.
Curr Protoc Cell Biol. 79(1):e51.
2017
Wang C
,
Ward ME
,
Chen R
,
Liu K
,
Tracy TE
,
Chen X
,
Xie M
,
Sohn PDongmin
,
Ludwig C
,
Meyer-Franke A
et al.
. 2017.
Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.
.
Stem Cell Reports. 9(4):1221-1233.
Krencik R
,
Seo K
,
van Asperen JV
,
Basu N
,
Cvetkovic C
,
Barlas S
,
Chen R
,
Ludwig C
,
Wang C
,
Ward ME
et al.
. 2017.
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.
.
Stem Cell Reports. 9(6):1745-1753.
2016
Tracy TE
,
Sohn PDongmin
,
S Minami S
,
Wang C
,
Min S-W
,
Li Y
,
Zhou Y
,
Le D
,
Lo I
,
Ponnusamy R
et al.
. 2016.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
.
Neuron. 90(2):245-60.
2015
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
2014
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.
2013
Grinberg LTenenholz
,
Wang X
,
Wang C
,
Sohn PDongmin
,
Theofilas P
,
Sidhu M
,
Arevalo JBenjamin
,
Heinsen H
,
Huang EJ
,
Rosen H
et al.
. 2013.
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
.
Acta Neuropathol. 125(4):581-93.
2012
Wang C
,
Sun B
,
Zhou Y
,
Grubb A
,
Gan L
. 2012.
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.
.
J Biol Chem. 287(47):39834-41.
2011
Kauppinen TM
,
Suh SWon
,
Higashi Y
,
Berman AE
,
Escartin C
,
Won SJoon
,
Wang C
,
Cho S-H
,
Gan L
,
Swanson RA
. 2011.
Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.
.
J Neuroinflammation. 8:152.