Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 330 results
Author Title [ Type(Desc)] Year
Journal Article
Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML et al..  2008.  Application of a translational profiling approach for the comparative analysis of CNS cell types.. Cell. 135(4):749-62.
Grinberg LTenenholz, Wang X, Wang C, Sohn PDongmin, Theofilas P, Sidhu M, Arevalo JBenjamin, Heinsen H, Huang EJ, Rosen H et al..  2013.  Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.. Acta Neuropathol. 125(4):581-93.
Auclair JR, Salisbury JP, Johnson JL, Petsko GA, Ringe D, Bosco DA, Agar NYR, Santagata S, Durham HD, Agar JN.  2014.  Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.. Proteomics. 14(10):1152-7.
Limbad C, Oron TRonnen, Alimirah F, Davalos AR, Tracy TE, Gan L, Desprez P-Y, Campisi J.  2020.  Astrocyte senescence promotes glutamate toxicity in cortical neurons.. PLoS One. 15(1):e0227887.
Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu G-Q, Adame A et al..  2015.  Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.. Nat Neurosci. 18(3):423-34.
Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC.  2011.  An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.. EMBO J. 30(14):2908-19.
Naseri N, Sharma M, Velinov M.  2020.  Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis.. Clin Genet.
Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC.  2001.  B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.. J Exp Med. 193(1):13-23.
Schmidt EF, Kus L, Gong S, Heintz N.  2013.  BAC transgenic mice and the GENSAT database of engineered mouse strains.. Cold Spring Harb Protoc. 2013(3)
Kim U, Qin XF, Gong S, Stevens S, Luo Y, Nussenzweig M, Roeder RG.  1996.  The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes.. Nature. 383(6600):542-7.
McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong W-X, Yue Z.  2014.  Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.. PLoS Genet. 10(10):e1004626.
Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM-Y.  2010.  A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.. Am J Pathol. 177(4):1977-88.
Ayed M, Lim H, Xie L.  2019.  Biological representation of chemicals using latent target interaction profile.. BMC Bioinformatics. 20(Suppl 24):674.
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG et al..  2018.  Bone protection by inhibition of microRNA-182.. Nat Commun. 9(1):4108.
DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM.  2002.  Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.. Science. 295(5563):2264-7.
Acosta-Ruiz A, Gutzeit VA, Skelly MJane, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J et al..  2020.  Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.. Neuron. 105(3):446-463.e13.
Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC.  2008.  CASK Functions as a Mg2+-independent neurexin kinase.. Cell. 133(2):328-39.
Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG.  2000.  The catalytic pathway of cytochrome p450cam at atomic resolution.. Science. 287(5458):1615-22.
Wang C, Sun B, Zhou Y, Grubb A, Gan L.  2012.  Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.. J Biol Chem. 287(47):39834-41.
Burré J, Sharma M, Südhof TC.  2018.  Cell Biology and Pathophysiology of α-Synuclein.. Cold Spring Harb Perspect Med. 8(3)
Gan L, Hahn SJ, Kaczmarek LK.  1999.  Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter.. J Neurochem. 73(4):1350-62.
Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P.  2008.  Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.. Nat Neurosci. 11(8):932-9.
Benharouga M, Sharma M, Lukacs GL.  2002.  CFTR folding and maturation in cells.. Methods Mol Med. 70:229-43.
Bales KR, Tzavara ET, Wu S, Wade MR, Bymaster FP, Paul SM, Nomikos GG.  2006.  Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.. J Clin Invest. 116(3):825-32.
Gan L, Perney TM, Kaczmarek LK.  1996.  Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons.. J Biol Chem. 271(10):5859-65.