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Xie L
,
Xie L
. 2019.
Pathway-Centric Structure-Based Multi-Target Compound Screening for Anti-Virulence Drug Repurposing.
.
Int J Mol Sci. 20(14)
Xie YXue
,
Naseri NN
,
Fels J
,
Kharel P
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Na Y
,
Lane D
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Burré J
,
Sharma M
. 2022.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
.
Nat Commun. 13(1):4918.
Xu X
,
Yang D
,
Wyss-Coray T
,
Yan J
,
Gan L
,
Sun Y
,
Mucke L
. 1999.
Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis.
.
Proc Natl Acad Sci U S A. 96(13):7547-52.
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Y
Yan Y
,
Wang X
,
Chaput D
,
Shin M-K
,
Koh Y
,
Gan L
,
Pieper AA
,
Woo J-AA
,
Kang DE
. 2022.
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women.
.
Cell. 185(21):3913-3930.e19.
X Yang W
,
Gong S
. 2005.
An overview on the generation of BAC transgenic mice for neuroscience research.
.
Curr Protoc Neurosci. Chapter 5:Unit5.20.
Yang X
,
Wen J
,
Yang H
,
Jones IR
,
Zhu X
,
Liu W
,
Li B
,
Clelland CD
,
Luo W
,
Wong MYing
et al.
. 2023.
Functional characterization of Alzheimer's disease genetic variants in microglia.
.
Nat Genet. 55(10):1735-1744.
Yang Z
,
Jiang H
,
Chaichanasakul T
,
Chachainasakul T
,
Gong S
,
Yang XWilliam
,
Heintz N
,
Lin S
. 2006.
Modified bacterial artificial chromosomes for zebrafish transgenesis.
.
Methods. 39(3):183-8.
Yang F
,
Li J
,
Song Y
,
Zhao M
,
Niemeyer JE
,
Luo P
,
Li D
,
Lin W
,
Ma H
,
Schwartz TH
. 2021.
Mesoscopic Mapping of Ictal Neurovascular Coupling in Awake Behaving Mice Using Optical Spectroscopy and Genetically Encoded Calcium Indicators.
.
Front Neurosci. 15:704834.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 92(1):252-264.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 90(4):724-39.
Z
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
Zhan L
,
Fan L
,
Kodama L
,
Sohn PDongmin
,
Wong MYing
,
Mousa GAlzaem
,
Zhou Y
,
Li Y
,
Gan L
. 2020.
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
.
Elife. 9
Zhang F
,
Wang S
,
Gan L
,
Vosler PS
,
Gao Y
,
Zigmond MJ
,
Chen J
. 2011.
Protective effects and mechanisms of sirtuins in the nervous system.
.
Prog Neurobiol. 95(3):373-95.
Zhang S
,
Liu Y
,
Xie L
. 2023.
A universal framework for accurate and efficient geometric deep learning of molecular systems.
.
Sci Rep. 13(1):19171.
Zhao L
,
Lin S
,
Bales KR
,
Gelfanova V
,
Koger D
,
DeLong C
,
Hale J
,
Liu F
,
Hunter JM
,
Paul SM
. 2009.
Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.
.
J Neurosci. 29(11):3603-12.
Zhao L
,
Gottesdiener AJ
,
Parmar M
,
Li M
,
Kaminsky SM
,
Chiuchiolo MJ
,
Sondhi D
,
Sullivan PM
,
Holtzman DM
,
Crystal RG
et al.
. 2016.
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
.
Neurobiol Aging. 44:159-72.
Zheng X
,
Wu B
,
Liu Y
,
Simmons SK
,
Kim K
,
Clarke GS
,
Ashiq A
,
Park J
,
Li J
,
Wang Z
et al.
. 2024.
Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.
.
Cell. 187(13):3236-3248.e21.
Zhou W
,
Zhu M
,
Wilson MA
,
Petsko GA
,
Fink AL
. 2006.
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
.
J Mol Biol. 356(4):1036-48.
Zhou Y
,
Su Y
,
Li B
,
Liu F
,
Ryder JW
,
Wu X
,
Gonzalez-DeWhitt PA
,
Gelfanova V
,
Hale JE
,
May PC
et al.
. 2003.
Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho.
.
Science. 302(5648):1215-7.
Zhu PK
,
W Zheng S
,
Zhang P
,
Jing M
,
Borden PM
,
Ali F
,
Guo K
,
Feng J
,
Marvin JS
,
Wang Y
et al.
. 2020.
Nanoscopic Visualization of Restricted Nonvolume Cholinergic and Monoaminergic Transmission with Genetically Encoded Sensors.
.
Nano Lett. 20(6):4073-4083.
Zimmer TS
,
Orr AL
,
Orr AG
. 2024.
Astrocytes in selective vulnerability to neurodegenerative disease.
.
Trends Neurosci. 47(4):289-302.
Zorumski CF
,
Paul SM
,
Izumi Y
,
Covey DF
,
Mennerick S
. 2013.
Neurosteroids, stress and depression: potential therapeutic opportunities.
.
Neurosci Biobehav Rev. 37(1):109-22.
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