Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 442 results

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM-Y. 2010. A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.. Am J Pathol. 177(4):1977-88.

Ayed M, Lim H, Xie L. 2019. Biological representation of chemicals using latent target interaction profile.. BMC Bioinformatics. 20(Suppl 24):674.

Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG et al.. 2018. Bone protection by inhibition of microRNA-182.. Nat Commun. 9(1):4108.

Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D. 2025. Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer's Disease.. bioRxiv.

Uekawa K, Hattori Y, Ahn SJi, Seo J, Casey N, Anfray A, Zhou P, Luo W, Anrather J, Park L et al.. 2023. Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.. Mol Neurodegener. 18(1):73.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. 2002. Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.. Science. 295(5563):2264-7.

Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al.. 2025. Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.

Acosta-Ruiz A, Gutzeit VA, Skelly MJane, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J et al.. 2020. Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.. Neuron. 105(3):446-463.e13.

Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC. 2008. CASK Functions as a Mg2+-independent neurexin kinase.. Cell. 133(2):328-39.

Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. 2000. The catalytic pathway of cytochrome p450cam at atomic resolution.. Science. 287(5458):1615-22.

Wang C, Sun B, Zhou Y, Grubb A, Gan L. 2012. Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.. J Biol Chem. 287(47):39834-41.

Rodriguez-Rodriguez P, Arroyo-Garcia LEnrique, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC et al.. 2024. A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.. Brain. 147(7):2384-2399.

Burré J, Sharma M, Südhof TC. 2018. Cell Biology and Pathophysiology of α-Synuclein.. Cold Spring Harb Perspect Med. 8(3)

Gan L, Hahn SJ, Kaczmarek LK. 1999. Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter.. J Neurochem. 73(4):1350-62.

Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. 2008. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.. Nat Neurosci. 11(8):932-9.

Bravo CParra, Naguib SA, Gan L. 2024. Cellular and pathological functions of tau.. Nat Rev Mol Cell Biol. 25(11):845-864.

Burré J, Sharma M. 2022. Cellular And Small Animal Models Of Neurodegenerative Diseases.. J Vis Exp. (186)

Benharouga M, Sharma M, Lukacs GL. 2002. CFTR folding and maturation in cells.. Methods Mol Med. 70:229-43.

Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al.. 2026. cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.

Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al.. 2026. cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.

Khawaja RR, Griego E, Lindenau K, Salek A, Gambardella J, Scrivo A, Monday HR, Bourdenx M, Madero-Pérez J, Khan ZN et al.. 2025. Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome.. Nat Cell Biol. 27(10):1688-1707.

Pfau SJ, Langen UH, Fisher TM, Prakash I, Nagpurwala F, Lozoya RA, Lee W-CAllen, Wu Z, Gu C. 2024. Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.. Nat Neurosci. 27(10):1892-1903.

Pham T-H, Qiu Y, Liu J, Zimmer S, O'Neill E, Xie L, Zhang P. 2022. Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing.. Patterns (N Y). 3(4):100441.

Iannone AF, Akgül G, Zhang R, Wacks S, Hussein N, Macias CGinelly, Donatelle A, Bauriedel JMJ, Wright C, Abramov D et al.. 2024. The chemokine Cxcl14 regulates interneuron differentiation in layer I of the somatosensory cortex.. Cell Rep. 43(8):114531.

Bales KR, Tzavara ET, Wu S, Wade MR, Bymaster FP, Paul SM, Nomikos GG. 2006. Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.. J Clin Invest. 116(3):825-32.