Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 330 results

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

R

Benharouga M, Sharma M, So J, Haardt M, Drzymala L, Popov M, Schwapach B, Grinstein S, Du K, Lukacs GL. 2003. The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia.. J Biol Chem. 278(24):22079-89.

Brand MD, Orr AL, Perevoshchikova IV, Quinlan CL. 2013. The role of mitochondrial function and cellular bioenergetics in ageing and disease.. Br J Dermatol. 169 Suppl 2:1-8.

Parmar MS, Jaumotte JD, Wyrostek SL, Zigmond MJ, Cavanaugh JE. 2014. The role of ERK1, 2, and 5 in dopamine neuron survival during aging.. Neurobiol Aging. 35(3):669-79.

Cissé M, Halabisky B, Harris J, Devidze N, Dubal DB, Sun B, Orr A, Lotz G, Kim DH, Hamto P et al.. 2011. Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.. Nature. 469(7328):47-52.

Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CAA, Whim MD, Yang B. 2005. Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.. Hear Res. 206(1-2):133-45.

Gong S, Nussenzweig MC. 1996. Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.. Science. 272(5260):411-4.

Orr AL, Quinlan CL, Perevoshchikova IV, Brand MD. 2012. A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.. J Biol Chem. 287(51):42921-35.

Birket MJ, Orr AL, Gerencser AA, Madden DT, Vitelli C, Swistowski A, Brand MD, Zeng X. 2011. A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.. J Cell Sci. 124(Pt 3):348-58.

S Minami S, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee C-H, Li J, Donnelly-Roberts D, Gan L. 2015. Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.. Biochem Pharmacol. 97(4):454-462.

Shin M-K, Vázquez-Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón-Pérez CJ, Barker S, Miller E, Franke K, Noterman MF et al.. 2021. Reducing acetylated tau is neuroprotective in brain injury.. Cell.

Medrihan L, Umschweif G, Sinha A, Reed S, Lee J, Gindinova K, Sinha SC, Greengard P, Sagi Y. 2020. Reduced Kv3.1 Activity in Dentate Gyrus Parvalbumin Cells Induces Vulnerability to Depression.. Biol Psychiatry. 88(5):405-414.

Witten IB, Steinberg EE, Lee SYeun, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C et al.. 2011. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.. Neuron. 72(5):721-33.

Kumar S, Singh SKumar, Viswakarma N, Sondarva G, Nair RSathish, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G et al.. 2020. Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells.. J Immunother Cancer. 8(2)

Lim H, He D, Qiu Y, Krawczuk P, Sun X, Xie L. 2019. Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology.. PLoS Comput Biol. 15(6):e1006619.

Rohan ML, Yamamoto RT, Ravichandran CT, Cayetano KR, Morales OG, Olson DP, Vitaliano G, Paul SM, Cohen BM. 2014. Rapid mood-elevating effects of low field magnetic stimulation in depression.. Biol Psychiatry. 76(3):186-93.

Gong S, Kus L, Heintz N. 2010. Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis.. Nat Protoc. 5(10):1678-96.

Q

Sigala PA, Fafarman AT, Schwans JP, Fried SD, Fenn TD, Caaveiro JMM, Pybus B, Ringe D, Petsko GA, Boxer SG et al.. 2013. Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.. Proc Natl Acad Sci U S A. 110(28):E2552-61.

P

Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM et al.. 2022. The Purkinje-myocardial junction is the anatomical origin of ventricular arrhythmia in CPVT.. JCI Insight.

Lai CF, Gong SC, Esteban M. 1991. The purified 14-kilodalton envelope protein of vaccinia virus produced in Escherichia coli induces virus immunity in animals.. J Virol. 65(10):5631-5.

A Willsey J, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA et al.. 2018. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.. Cell. 174(3):505-520.

Zhan L, Krabbe G, Du F, Jones I, Reichert MC, Telpoukhovskaia M, Kodama L, Wang C, Cho S-H, Sayed F et al.. 2019. Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.. PLoS Biol. 17(2):e3000134.

Bosco DA, LaVoie MJ, Petsko GA, Ringe D. 2011. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.. Cold Spring Harb Perspect Biol. 3(10):a007500.

Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J. 2011. Protective effects and mechanisms of sirtuins in the nervous system.. Prog Neurobiol. 95(3):373-95.

Sharma M, Burré J, Südhof TC. 2012. Proteasome inhibition alleviates SNARE-dependent neurodegeneration.. Sci Transl Med. 4(147):147ra113.

Burré J, Vivona S, Diao J, Sharma M, Brunger AT, Südhof TC. 2013. Properties of native brain α-synuclein.. Nature. 498(7453):E4-6;discussionE6-7.