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Found 397 results
Author
Title
[
Type
]
Year
Journal Article
Bravo CParra
,
Giani AMaria
,
Madero-Pérez J
,
Zhao Z
,
Wan Y
,
Samelson AJ
,
Wong MYing
,
Evangelisti A
,
Cordes E
,
Fan L
et al.
. 2024.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
.
Cell. 187(10):2446-2464.e22.
Faraco G
,
Park L
,
Zhou P
,
Luo W
,
Paul SM
,
Anrather J
,
Iadecola C
. 2016.
Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.
.
J Cereb Blood Flow Metab. 36(1):241-52.
Burré J
,
Zimmermann H
,
Volknandt W
. 2007.
Identification and characterization of SV31, a novel synaptic vesicle membrane protein and potential transporter.
.
J Neurochem. 103(1):276-87.
Gan L
,
Ye S
,
Chu A
,
Anton K
,
Yi S
,
Vincent VA
,
von Schack D
,
Chin D
,
Murray J
,
Lohr S
et al.
. 2004.
Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.
.
J Biol Chem. 279(7):5565-72.
Sun B
,
Halabisky B
,
Zhou Y
,
Palop JJ
,
Yu G
,
Mucke L
,
Gan L
. 2009.
Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.
.
Cell Stem Cell. 5(6):624-33.
Dodart J-C
,
Bales KR
,
Gannon KS
,
Greene SJ
,
DeMattos RB
,
Mathis C
,
DeLong CA
,
Wu S
,
Wu X
,
Holtzman DM
et al.
. 2002.
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
.
Nat Neurosci. 5(5):452-7.
Burré J
,
Zimmermann H
,
Volknandt W
. 2007.
Immunoisolation and subfractionation of synaptic vesicle proteins.
.
Anal Biochem. 362(2):172-81.
Morciano M
,
Burré J
,
Corvey C
,
Karas M
,
Zimmermann H
,
Volknandt W
. 2005.
Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis.
.
J Neurochem. 95(6):1732-45.
Li X-J
,
Orr AL
,
Li S
. 2010.
Impaired mitochondrial trafficking in Huntington's disease.
.
Biochim Biophys Acta. 1802(1):62-5.
Hansen KB
,
Mullasseril P
,
Dawit S
,
Kurtkaya NL
,
Yuan H
,
Vance KM
,
Orr AG
,
Kvist T
,
Ogden KK
,
Le P
et al.
. 2010.
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
.
J Pharmacol Exp Ther. 333(3):650-62.
Sang T-K
,
Li C
,
Liu W
,
Rodriguez A
,
Abrams JM
,
S Zipursky L
,
Jackson GR
. 2005.
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.
.
Hum Mol Genet. 14(3):357-72.
Ward ME
,
Chen R
,
Huang H-Y
,
Ludwig C
,
Telpoukhovskaia M
,
Taubes A
,
Boudin H
,
Minami SS
,
Reichert M
,
Albrecht P
et al.
. 2017.
Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
.
Sci Transl Med. 9(385)
Boselli M
,
Lee B-H
,
Robert J
,
Prado MA
,
Min S-W
,
Cheng C
,
M Silva C
,
Seong C
,
Elsasser S
,
Hatle KM
et al.
. 2017.
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.
.
J Biol Chem. 292(47):19209-19225.
Orr AL
,
Ashok D
,
Sarantos MR
,
Shi T
,
Hughes RE
,
Brand MD
. 2013.
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening.
.
Free Radic Biol Med. 65:1047-1059.
Orr AG
,
Sharma A
,
Binder NB
,
Miller AH
,
Pearce BD
. 2010.
Interleukin-1 mediates long-term hippocampal dentate granule cell loss following postnatal viral infection.
.
J Mol Neurosci. 41(1):89-96.
Esposito L
,
Gan L
,
Yu G-Q
,
Essrich C
,
Mucke L
. 2004.
Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.
.
J Neurochem. 91(6):1260-74.
Zhao L
,
Gottesdiener AJ
,
Parmar M
,
Li M
,
Kaminsky SM
,
Chiuchiolo MJ
,
Sondhi D
,
Sullivan PM
,
Holtzman DM
,
Crystal RG
et al.
. 2016.
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
.
Neurobiol Aging. 44:159-72.
Orr AG
,
Lo I
,
Schumacher H
,
Ho K
,
Gill M
,
Guo W
,
Kim DH
,
Knox A
,
Saito T
,
Saido TC
et al.
. 2018.
Istradefylline reduces memory deficits in aging mice with amyloid pathology.
.
Neurobiol Dis. 110:29-36.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2024.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
J Clin Invest. 134(3)
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2023.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
bioRxiv.
Huang Y
,
Shenoy S
,
Lu B
,
Liu W
,
Li C
. 2012.
Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.
.
J Neurogenet. 26(2):158-67.
Bales KR
,
Verina T
,
Dodel RC
,
Du Y
,
Altstiel L
,
Bender M
,
Hyslop P
,
Johnstone EM
,
Little SP
,
Cummins DJ
et al.
. 1997.
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
.
Nat Genet. 17(3):263-4.
Heintz N
,
Gong S
. 2019.
Large-Scale Preparation and Linearization of Bacterial Artificial Chromosome (BAC) DNA.
.
Cold Spring Harb Protoc. 2019(11)
Bharadwaj PR
,
Verdile G
,
Barr RK
,
Gupta V
,
Steele JW
,
M Lachenmayer L
,
Yue Z
,
Ehrlich ME
,
Petsko G
,
Ju S
et al.
. 2012.
Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
.
J Alzheimers Dis. 32(4):949-67.
Steele JW
,
Lachenmayer ML
,
Ju S
,
Stock A
,
Liken J
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
.
Mol Psychiatry. 18(8):889-97.
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