Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 410 results
[ Author(Desc)] Title Type Year
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Inda MCarmen, Joshi S, Wang T, Bolaender A, Gandu S, Iii JKoren, Che AYue, Taldone T, Yan P, Sun W et al..  2020.  The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.. Nat Commun. 11(1):319.
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG et al..  2018.  Bone protection by inhibition of microRNA-182.. Nat Commun. 9(1):4108.
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Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK.  1998.  Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.. Nat Neurosci. 1(6):462-9.
Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S et al..  2011.  A yeast model of FUS/TLS-dependent cytotoxicity.. PLoS Biol. 9(4):e1001052.
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Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CAA, Whim MD, Yang B.  2005.  Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.. Hear Res. 206(1-2):133-45.
Kanemasa T, Gan L, Perney TM, Wang LY, Kaczmarek LK.  1995.  Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts.. J Neurophysiol. 74(1):207-17.
Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PDongmin, Bowles KR et al..  2019.  A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.. Stem Cell Reports.
Kauppinen TM, Suh SWon, Higashi Y, Berman AE, Escartin C, Won SJoon, Wang C, Cho S-H, Gan L, Swanson RA.  2011.  Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.. J Neuroinflammation. 8:152.
Kauppinen TM, Gan L, Swanson RA.  2013.  Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.. Biochim Biophys Acta. 1833(8):1985-91.
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al..  2023.  KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. bioRxiv.
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al..  2024.  KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. J Clin Invest. 134(3)
Kember RL, Georgi B, Bailey-Wilson JE, Stambolian D, Paul SM, Bućan M.  2015.  Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder.. BMC Genet. 16:27.
Kim KHye, Liu J, Galvin RJSells, Dage JL, Egeland JA, Smith RC, Merchant KM, Paul SM.  2015.  Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.. PLoS One. 10(11):e0142693.
Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM.  2009.  Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.. Neuron. 64(5):632-44.
Kim U, Qin XF, Gong S, Stevens S, Luo Y, Nussenzweig M, Roeder RG.  1996.  The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes.. Nature. 383(6600):542-7.
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC et al..  2019.  Microglial microRNAs mediate sex-specific responses to tau pathology.. Nat Neurosci.
Kodama L, Gan L.  2019.  Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases? Trends Mol Med.
Koistinaho M, Lin S, Wu X, Esterman M, Koger D, Hanson J, Higgs R, Liu F, Malkani S, Bales KR et al..  2004.  Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.. Nat Med. 10(7):719-26.
Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR et al..  2024.  Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.. PNAS Nexus. 3(5):pgae179.
Krabbe G, S Minami S, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC et al..  2017.  Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.
Kreinbring CA, Remillard SP, Hubbard P, Brodkin HR, Leeper FJ, Hawksley D, Lai EY, Fulton C, Petsko GA, Ringe D.  2014.  Structure of a eukaryotic thiaminase I.. Proc Natl Acad Sci U S A. 111(1):137-42.
Krencik R, Seo K, van Asperen JV, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME et al..  2017.  Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.. Stem Cell Reports. 9(6):1745-1753.
Kronin V, Wu L, Gong S, Nussenzweig MC, Shortman K.  2000.  DEC-205 as a marker of dendritic cells with regulatory effects on CD8 T cell responses.. Int Immunol. 12(5):731-5.
Kumar S, Singh SKumar, Viswakarma N, Sondarva G, Nair RSathish, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G et al..  2020.  Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells.. J Immunother Cancer. 8(2)