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Found 31 results
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2023
Samelson AJ
,
Ariqat N
,
McKetney J
,
Rohanitazangi G
,
Bravo CParra
,
Goodness D
,
Tian R
,
Grosjean P
,
Abskharon R
,
Eisenberg D
et al.
. 2023.
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
.
bioRxiv.
2022
Burré J
,
Sharma M
. 2022.
Cellular And Small Animal Models Of Neurodegenerative Diseases.
.
J Vis Exp. (186)
Pham T-H
,
Qiu Y
,
Liu J
,
Zimmer S
,
O'Neill E
,
Xie L
,
Zhang P
. 2022.
Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing.
.
Patterns (N Y). 3(4):100441.
Dräger NM
,
Sattler SM
,
Huang CTzu-Ling
,
Teter OM
,
Leng K
,
Hashemi SHadi
,
Hong J
,
Aviles G
,
Clelland CD
,
Zhan L
et al.
. 2022.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
.
Nat Neurosci.
2019
Naseri NN
,
Wang H
,
Guo J
,
Sharma M
,
Luo W
. 2019.
The complexity of tau in Alzheimer's disease.
.
Neurosci Lett. 705:183-194.
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
2018
Burré J
,
Sharma M
,
Südhof TC
. 2018.
Cell Biology and Pathophysiology of α-Synuclein.
.
Cold Spring Harb Perspect Med. 8(3)
Gan L
,
Cookson MR
,
Petrucelli L
,
La Spada AR
. 2018.
Converging pathways in neurodegeneration, from genetics to mechanisms.
.
Nat Neurosci. 21(10):1300-1309.
2016
Möller T
,
Bard F
,
Bhattacharya A
,
Biber K
,
Campbell B
,
Dale E
,
Eder C
,
Gan L
,
Garden GA
,
Hughes ZA
et al.
. 2016.
Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.
.
Glia. 64(10):1788-94.
2015
Kember RL
,
Georgi B
,
Bailey-Wilson JE
,
Stambolian D
,
Paul SM
,
Bućan M
. 2015.
Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder.
.
BMC Genet. 16:27.
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
2013
Edayathumangalam R
,
Wu R
,
Garcia R
,
Wang Y
,
Wang W
,
Kreinbring CA
,
Bach A
,
Liao J
,
Stone TA
,
Terwilliger TC
et al.
. 2013.
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
.
Proc Natl Acad Sci U S A. 110(44):17820-5.
Wu X
,
Gong S
,
Roy-Burman P
,
Lee P
,
Culig Z
. 2013.
Current mouse and cell models in prostate cancer research.
.
Endocr Relat Cancer. 20(4):R155-70.
2012
Wang C
,
Sun B
,
Zhou Y
,
Grubb A
,
Gan L
. 2012.
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.
.
J Biol Chem. 287(47):39834-41.
Davies CW
,
Chaney J
,
Korbel G
,
Ringe D
,
Petsko GA
,
Ploegh H
,
Das C
. 2012.
The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK).
.
Bioorg Med Chem Lett. 22(12):3900-4.
Pranski EL
,
Van Sanford CD
,
Dalal NV
,
Orr AL
,
Karmali D
,
Cooper DS
,
Costa N
,
Heilman CJ
,
Gearing M
,
Lah JJ
et al.
. 2012.
Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.
.
Neurosci Lett. 520(1):104-9.
Sharma M
,
Burré J
,
Bronk P
,
Zhang Y
,
Xu W
,
Südhof TC
. 2012.
CSPα knockout causes neurodegeneration by impairing SNAP-25 function.
.
EMBO J. 31(4):829-41.
2011
Sharma M
,
Burré J
,
Südhof TC
. 2011.
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.
.
Nat Cell Biol. 13(1):30-9.
Cho S-H
,
Sun B
,
Zhou Y
,
Kauppinen TM
,
Halabisky B
,
Wes P
,
Ransohoff RM
,
Gan L
. 2011.
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.
.
J Biol Chem. 286(37):32713-22.
2008
Mukherjee K
,
Sharma M
,
Urlaub H
,
Bourenkov GP
,
Jahn R
,
Südhof TC
,
Wahl MC
. 2008.
CASK Functions as a Mg2+-independent neurexin kinase.
.
Cell. 133(2):328-39.
Bateup HS
,
Svenningsson P
,
Kuroiwa M
,
Gong S
,
Nishi A
,
Heintz N
,
Greengard P
. 2008.
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
.
Nat Neurosci. 11(8):932-9.
Sun B
,
Zhou Y
,
Halabisky B
,
Lo I
,
Cho S-H
,
Mueller-Steiner S
,
Devidze N
,
Wang X
,
Grubb A
,
Gan L
. 2008.
Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease.
.
Neuron. 60(2):247-57.
2006
Bales KR
,
Tzavara ET
,
Wu S
,
Wade MR
,
Bymaster FP
,
Paul SM
,
Nomikos GG
. 2006.
Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.
.
J Clin Invest. 116(3):825-32.
2002
Benharouga M
,
Sharma M
,
Lukacs GL
. 2002.
CFTR folding and maturation in cells.
.
Methods Mol Med. 70:229-43.
DeMattos RB
,
O'dell MA
,
Parsadanian M
,
Taylor JW
,
Harmony JAK
,
Bales KR
,
Paul SM
,
Aronow BJ
,
Holtzman DM
. 2002.
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 99(16):10843-8.
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