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Found 36 results
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1991
Lai CF
,
Gong SC
,
Esteban M
. 1991.
The purified 14-kilodalton envelope protein of vaccinia virus produced in Escherichia coli induces virus immunity in animals.
.
J Virol. 65(10):5631-5.
2001
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Dodart JC
,
Paul SM
,
Holtzman DM
. 2001.
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 98(15):8850-5.
2003
Luo W-jie
,
Wang H
,
Li H
,
Kim BS
,
Shah S
,
Lee H-J
,
Thinakaran G
,
Kim T-W
,
Yu G
,
Xu H
. 2003.
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.
.
J Biol Chem. 278(10):7850-4.
2004
Canet-Avilés RM
,
Wilson MA
,
Miller DW
,
Ahmad R
,
McLendon C
,
Bandyopadhyay S
,
Baptista MJ
,
Ringe D
,
Petsko GA
,
Cookson MR
. 2004.
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
.
Proc Natl Acad Sci U S A. 101(24):9103-8.
2005
Gu X
,
Li C
,
Wei W
,
Lo V
,
Gong S
,
Li S-H
,
Iwasato T
,
Itohara S
,
Li X-J
,
Mody I
et al.
. 2005.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
.
Neuron. 46(3):433-44.
2007
Tomishima MJ
,
Hadjantonakis A-K
,
Gong S
,
Studer L
. 2007.
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library.
.
Stem Cells. 25(1):39-45.
2008
Gan L
,
Mucke L
. 2008.
Paths of convergence: sirtuins in aging and neurodegeneration.
.
Neuron. 58(1):10-4.
Sanchez-Mejia RO
,
Newman JW
,
Toh S
,
Yu G-Q
,
Zhou Y
,
Halabisky B
,
Cissé M
,
Scearce-Levie K
,
Cheng IH
,
Gan L
et al.
. 2008.
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.
.
Nat Neurosci. 11(11):1311-8.
Mannaioni G
,
Orr AG
,
Hamill CE
,
Yuan H
,
Pedone KH
,
McCoy KL
,
Palmini RBerlinguer
,
Junge CE
,
C Lee J
,
Yepes M
et al.
. 2008.
Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.
.
J Biol Chem. 283(29):20600-11.
2010
Vives-Bauza C
,
Zhou C
,
Huang Y
,
Cui M
,
de Vries RLA
,
Kim J
,
May J
,
Tocilescu MAleksandra
,
Liu W
,
Ko HSeok
et al.
. 2010.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
.
Proc Natl Acad Sci U S A. 107(1):378-83.
Lewandowski NM
,
Ju S
,
Verbitsky M
,
Ross B
,
Geddie ML
,
Rockenstein E
,
Adame A
,
Muhammad A
,
Vonsattel JPaul
,
Ringe D
et al.
. 2010.
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
.
Proc Natl Acad Sci U S A. 107(39):16970-5.
2011
Liu W
,
Acín-Peréz R
,
Geghman KD
,
Manfredi G
,
Lu B
,
Li C
. 2011.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.
.
Proc Natl Acad Sci U S A. 108(31):12920-4.
Kauppinen TM
,
Suh SWon
,
Higashi Y
,
Berman AE
,
Escartin C
,
Won SJoon
,
Wang C
,
Cho S-H
,
Gan L
,
Swanson RA
. 2011.
Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.
.
J Neuroinflammation. 8:152.
Zhang F
,
Wang S
,
Gan L
,
Vosler PS
,
Gao Y
,
Zigmond MJ
,
Chen J
. 2011.
Protective effects and mechanisms of sirtuins in the nervous system.
.
Prog Neurobiol. 95(3):373-95.
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
2012
Martens LHerl
,
Zhang J
,
Barmada SJ
,
Zhou P
,
Kamiya S
,
Sun B
,
Min S-W
,
Gan L
,
Finkbeiner S
,
Huang EJ
et al.
. 2012.
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
.
J Clin Invest. 122(11):3955-9.
Sharma M
,
Burré J
,
Südhof TC
. 2012.
Proteasome inhibition alleviates SNARE-dependent neurodegeneration.
.
Sci Transl Med. 4(147):147ra113.
2013
Liu CFeng
,
Liu D
,
Momb J
,
Thomas PW
,
Lajoie A
,
Petsko GA
,
Fast W
,
Ringe D
. 2013.
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.
.
Biochemistry. 52(9):1603-10.
Kauppinen TM
,
Gan L
,
Swanson RA
. 2013.
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
.
Biochim Biophys Acta. 1833(8):1985-91.
Auclair JR
,
Johnson JL
,
Liu Q
,
Salisbury JP
,
Rotunno MS
,
Petsko GA
,
Ringe D
,
Brown RH
,
Bosco DA
,
Agar JN
. 2013.
Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.
.
Biochemistry. 52(36):6137-44.
Burré J
,
Vivona S
,
Diao J
,
Sharma M
,
Brunger AT
,
Südhof TC
. 2013.
Properties of native brain α-synuclein.
.
Nature. 498(7453):E4-6;discussionE6-7.
2014
Mecozzi VJ
,
Berman DE
,
Simoes S
,
Vetanovetz C
,
Awal MR
,
Patel VM
,
Schneider RT
,
Petsko GA
,
Ringe D
,
Small SA
. 2014.
Pharmacological chaperones stabilize retromer to limit APP processing.
.
Nat Chem Biol. 10(6):443-9.
Strauss KA
,
Markx S
,
Georgi B
,
Paul SM
,
Jinks RN
,
Hoshi T
,
McDonald A
,
First MB
,
Liu W
,
Benkert AR
et al.
. 2014.
A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.
.
Hum Mol Genet. 23(23):6395-406.
Hey-Mogensen M
,
Goncalves RLS
,
Orr AL
,
Brand MD
. 2014.
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
.
Free Radic Biol Med. 72:149-55.
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.
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