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Found 5 results
Author
Title
Type
[
Year
]
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Author
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Qiu, Yue
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2023
Oliveros G
,
Wallace CH
,
Chaudry O
,
Liu Q
,
Qiu Y
,
Xie L
,
Rockwell P
,
Figueiredo-Pereira ME
,
Serrano PA
. 2023.
Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation.
.
Brain. 146(3):898-911.
2022
Pham T-H
,
Qiu Y
,
Liu J
,
Zimmer S
,
O'Neill E
,
Xie L
,
Zhang P
. 2022.
Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing.
.
Patterns (N Y). 3(4):100441.
Wu Y
,
Liu Q
,
Qiu Y
,
Xie L
. 2022.
Deep learning prediction of chemical-induced dose-dependent and context-specific multiplex phenotype responses and its application to personalized alzheimer's disease drug repurposing.
.
PLoS Comput Biol. 18(8):e1010367.
2021
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
2019
Lim H
,
He D
,
Qiu Y
,
Krawczuk P
,
Sun X
,
Xie L
. 2019.
Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology.
.
PLoS Comput Biol. 15(6):e1006619.