Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 444 results
Author [ Title(Asc)] Type Year
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Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Benharouga M, Sharma M, Lukacs GL.  2002.  CFTR folding and maturation in cells.. Methods Mol Med. 70:229-43.
Burré J, Sharma M.  2022.  Cellular And Small Animal Models Of Neurodegenerative Diseases.. J Vis Exp. (186)
Bravo CParra, Naguib SA, Gan L.  2024.  Cellular and pathological functions of tau.. Nat Rev Mol Cell Biol. 25(11):845-864.
Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P.  2008.  Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.. Nat Neurosci. 11(8):932-9.
Gan L, Hahn SJ, Kaczmarek LK.  1999.  Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter.. J Neurochem. 73(4):1350-62.
Burré J, Sharma M, Südhof TC.  2018.  Cell Biology and Pathophysiology of α-Synuclein.. Cold Spring Harb Perspect Med. 8(3)
Rodriguez-Rodriguez P, Arroyo-Garcia LEnrique, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC et al..  2024.  A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.. Brain. 147(7):2384-2399.
Wang C, Sun B, Zhou Y, Grubb A, Gan L.  2012.  Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.. J Biol Chem. 287(47):39834-41.
Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG.  2000.  The catalytic pathway of cytochrome p450cam at atomic resolution.. Science. 287(5458):1615-22.
Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC.  2008.  CASK Functions as a Mg2+-independent neurexin kinase.. Cell. 133(2):328-39.
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Acosta-Ruiz A, Gutzeit VA, Skelly MJane, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J et al..  2020.  Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.. Neuron. 105(3):446-463.e13.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM.  2002.  Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.. Science. 295(5563):2264-7.
Uekawa K, Hattori Y, Ahn SJi, Seo J, Casey N, Anfray A, Zhou P, Luo W, Anrather J, Park L et al..  2023.  Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.. Mol Neurodegener. 18(1):73.
Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D.  2025.  Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer's Disease.. bioRxiv.
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG et al..  2018.  Bone protection by inhibition of microRNA-182.. Nat Commun. 9(1):4108.
Ayed M, Lim H, Xie L.  2019.  Biological representation of chemicals using latent target interaction profile.. BMC Bioinformatics. 20(Suppl 24):674.
Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM-Y.  2010.  A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.. Am J Pathol. 177(4):1977-88.
McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong W-X, Yue Z.  2014.  Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.. PLoS Genet. 10(10):e1004626.
Kim U, Qin XF, Gong S, Stevens S, Luo Y, Nussenzweig M, Roeder RG.  1996.  The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes.. Nature. 383(6600):542-7.
Schmidt EF, Kus L, Gong S, Heintz N.  2013.  BAC transgenic mice and the GENSAT database of engineered mouse strains.. Cold Spring Harb Protoc. 2013(3)
Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC.  2001.  B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.. J Exp Med. 193(1):13-23.
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Naseri N, Sharma M, Velinov M.  2020.  Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis.. Clin Genet.
Amin S, Liu B, Gan L.  2023.  Autophagy prevents microglial senescence.. Nat Cell Biol. 25(7):923-925.