Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 376 results

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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Sun B, Gan L. 2011. Manipulation of gene expression in the central nervous system with lentiviral vectors.. Methods Mol Biol. 670:155-68.

Singh SKumar, Kumar S, Viswakarma N, Principe DR, Das S, Sondarva G, Nair RSathish, Srivastava P, Sinha SC, Grippo PJ et al.. 2021. MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.. Oncogene. 40(43):6153-6165.

Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M et al.. 2019. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.. Nat Genet. 51(8):1252-1262.

Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. 2012. Mass spectrometry tools for analysis of intermolecular interactions.. Methods Mol Biol. 896:387-98.

Syed I, Rathod J, Parmar M, Corcoran GB, Ray SD. 2012. Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury.. Mol Cell Biochem. 365(1-2):351-61.

Huang Y, Liu B, Sinha SC, Amin S, Gan L. 2023. Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.. Mol Neurodegener. 18(1):79.

Guiberson NGuy Lewis, Pineda A, Abramov D, Kharel P, Carnazza KE, Wragg RT, Dittman JS, Burré J. 2018. Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.. Nat Commun. 9(1):3986.

Lopez-Lee C, Torres ERuth S, Carling G, Gan L. 2024. Mechanisms of sex differences in Alzheimer's disease.. Neuron.

Choi DW, Armitage R, Brady LS, Coetzee T, Fisher W, Hyman S, Pande A, Paul S, Potter W, Roin B et al.. 2014. Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs.. Neuron. 84(3):554-63.

Yang F, Li J, Song Y, Zhao M, Niemeyer JE, Luo P, Li D, Lin W, Ma H, Schwartz TH. 2021. Mesoscopic Mapping of Ictal Neurovascular Coupling in Awake Behaving Mice Using Optical Spectroscopy and Genetically Encoded Calcium Indicators.. Front Neurosci. 15:704834.

Saura J, Petegnief V, Wu X, Liang Y, Paul SM. 2003. Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide.. J Neurochem. 85(6):1455-67.

Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul SM. 2015. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.. Sci Rep. 5:11161.

Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC et al.. 2019. Microglial microRNAs mediate sex-specific responses to tau pathology.. Nat Neurosci.

Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, Chin M, Li Y, Le D, Zhou Y et al.. 2022. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.. Nat Commun. 13(1):1969.

Krabbe G, S Minami S, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC et al.. 2017. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.

Acuna C, Guo Q, Burré J, Sharma M, Sun J, Südhof TC. 2014. Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.. Neuron. 82(5):1088-100.

Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT et al.. 2018. Military-related risk factors for dementia.. Alzheimers Dement. 14(12):1651-1662.

Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN. 2008. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.. Autism Res. 1(3):147-58.

Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H et al.. 2004. Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes.. J Cell Biol. 164(6):923-33.

Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD. 2012. Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.. J Biol Chem. 287(32):27255-64.

Bose A, M Beal F. 2016. Mitochondrial dysfunction in Parkinson's disease.. J Neurochem.

Kumar S, Singh SKumar, Viswakarma N, Sondarva G, Nair RSathish, Sethupathi P, Sinha SC, Emmadi R, Hoskins K, Danciu O et al.. 2020. Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.. Proc Natl Acad Sci U S A. 117(14):7961-7970.

Viswakarma N, Sondarva G, Principe DR, Nair RSathish, Kumar S, Singh SKumar, Das S, Sinha SC, Grippo PJ, Grimaldo S et al.. 2021. Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development.. Cancer Lett. 515:1-13.

Gong S, X Yang W. 2005. Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice.. Curr Protoc Neurosci. Chapter 5:Unit5.21.

Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XWilliam, Heintz N, Lin S. 2006. Modified bacterial artificial chromosomes for zebrafish transgenesis.. Methods. 39(3):183-8.