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P
Tomishima MJ
,
Hadjantonakis A-K
,
Gong S
,
Studer L
. 2007.
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library.
.
Stem Cells. 25(1):39-45.
Hey-Mogensen M
,
Goncalves RLS
,
Orr AL
,
Brand MD
. 2014.
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
.
Free Radic Biol Med. 72:149-55.
Martens LHerl
,
Zhang J
,
Barmada SJ
,
Zhou P
,
Kamiya S
,
Sun B
,
Min S-W
,
Gan L
,
Finkbeiner S
,
Huang EJ
et al.
. 2012.
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
.
J Clin Invest. 122(11):3955-9.
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.
Chen X
,
Li Y
,
Wang C
,
Tang Y
,
Mok S-A
,
Tsai RM
,
Rojas JC
,
Karydas A
,
Miller BL
,
Boxer AL
et al.
. 2020.
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
.
Mol Neurodegener. 15(1):2.
Burré J
,
Vivona S
,
Diao J
,
Sharma M
,
Brunger AT
,
Südhof TC
. 2013.
Properties of native brain α-synuclein.
.
Nature. 498(7453):E4-6;discussionE6-7.
Sharma M
,
Burré J
,
Südhof TC
. 2012.
Proteasome inhibition alleviates SNARE-dependent neurodegeneration.
.
Sci Transl Med. 4(147):147ra113.
Zhang F
,
Wang S
,
Gan L
,
Vosler PS
,
Gao Y
,
Zigmond MJ
,
Chen J
. 2011.
Protective effects and mechanisms of sirtuins in the nervous system.
.
Prog Neurobiol. 95(3):373-95.
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
Lai CF
,
Gong SC
,
Esteban M
. 1991.
The purified 14-kilodalton envelope protein of vaccinia virus produced in Escherichia coli induces virus immunity in animals.
.
J Virol. 65(10):5631-5.
Blackwell DJ
,
Faggioni M
,
Wleklinski MJ
,
Gomez-Hurtado N
,
Venkataraman R
,
Gibbs CE
,
Baudenbacher FJ
,
Gong S
,
Fishman GI
,
Boyle PM
et al.
. 2022.
The Purkinje-myocardial junction is the anatomical origin of ventricular arrhythmia in CPVT.
.
JCI Insight.
Q
Sigala PA
,
Fafarman AT
,
Schwans JP
,
Fried SD
,
Fenn TD
,
Caaveiro JMM
,
Pybus B
,
Ringe D
,
Petsko GA
,
Boxer SG
et al.
. 2013.
Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.
.
Proc Natl Acad Sci U S A. 110(28):E2552-61.
R
Gong S
,
Kus L
,
Heintz N
. 2010.
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis.
.
Nat Protoc. 5(10):1678-96.
Rohan ML
,
Yamamoto RT
,
Ravichandran CT
,
Cayetano KR
,
Morales OG
,
Olson DP
,
Vitaliano G
,
Paul SM
,
Cohen BM
. 2014.
Rapid mood-elevating effects of low field magnetic stimulation in depression.
.
Biol Psychiatry. 76(3):186-93.
Lim H
,
He D
,
Qiu Y
,
Krawczuk P
,
Sun X
,
Xie L
. 2019.
Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology.
.
PLoS Comput Biol. 15(6):e1006619.
Kumar S
,
Singh SKumar
,
Viswakarma N
,
Sondarva G
,
Nair RSathish
,
Sethupathi P
,
Dorman M
,
Sinha SC
,
Hoskins K
,
Thatcher G
et al.
. 2020.
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells.
.
J Immunother Cancer. 8(2)
Witten IB
,
Steinberg EE
,
Lee SYeun
,
Davidson TJ
,
Zalocusky KA
,
Brodsky M
,
Yizhar O
,
Cho SL
,
Gong S
,
Ramakrishnan C
et al.
. 2011.
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.
.
Neuron. 72(5):721-33.
Medrihan L
,
Umschweif G
,
Sinha A
,
Reed S
,
Lee J
,
Gindinova K
,
Sinha SC
,
Greengard P
,
Sagi Y
. 2020.
Reduced Kv3.1 Activity in Dentate Gyrus Parvalbumin Cells Induces Vulnerability to Depression.
.
Biol Psychiatry. 88(5):405-414.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
S Minami S
,
Shen V
,
Le D
,
Krabbe G
,
Asgarov R
,
Perez-Celajes L
,
Lee C-H
,
Li J
,
Donnelly-Roberts D
,
Gan L
. 2015.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
.
Biochem Pharmacol. 97(4):454-462.
Birket MJ
,
Orr AL
,
Gerencser AA
,
Madden DT
,
Vitelli C
,
Swistowski A
,
Brand MD
,
Zeng X
. 2011.
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.
.
J Cell Sci. 124(Pt 3):348-58.
Orr AL
,
Quinlan CL
,
Perevoshchikova IV
,
Brand MD
. 2012.
A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.
.
J Biol Chem. 287(51):42921-35.
Gong S
,
Nussenzweig MC
. 1996.
Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.
.
Science. 272(5260):411-4.
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