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Found 376 results
Author
Title
[
Type
]
Year
Journal Article
Xia D
,
Lianoglou S
,
Sandmann T
,
Calvert M
,
Suh JH
,
Thomsen E
,
Dugas J
,
Pizzo ME
,
DeVos SL
,
Earr TK
et al.
. 2022.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
.
Mol Neurodegener. 17(1):41.
Sexton CE
,
Bitan G
,
Bowles KR
,
Brys M
,
Buée L
,
Maina MBukar
,
Clelland CD
,
Cohen AD
,
Crary JF
,
Dage JL
et al.
. 2024.
Novel avenues of tau research.
.
Alzheimers Dement.
Orr AL
,
Ashok D
,
Sarantos MR
,
Ng R
,
Shi T
,
Gerencser AA
,
Hughes RE
,
Brand MD
. 2014.
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.
.
PLoS One. 9(2):e89938.
Orr AL
,
Li S
,
Wang C-E
,
Li H
,
Wang J
,
Rong J
,
Xu X
,
Mastroberardino PGiorgio
,
J Greenamyre T
,
Li X-J
. 2008.
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
.
J Neurosci. 28(11):2783-92.
Heintz N
,
Gong S
. 2020.
One-Step Bacterial Artificial Chromosome (BAC) Modification: Cloning of the A Homology Arm into Reporter-Shuttle Vector.
.
Cold Spring Harb Protoc. 2020(7):098111.
Heintz N
,
Gong S
. 2020.
One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of Plasmids.
.
Cold Spring Harb Protoc. 2020(7):098095.
Heintz N
,
Gong S
. 2020.
One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of the A Homology Arm (A-Box).
.
Cold Spring Harb Protoc. 2020(7):098103.
Heintz N
,
Gong S
. 2020.
One-Step Bacterial Artificial Chromosome (BAC) Modification: Transfer of the Reporter Vector into BAC/RecA Cells and Selection of Co-Integrates.
.
Cold Spring Harb Protoc. 2020(7):098137.
Heintz N
,
Gong S
. 2020.
One-Step Bacterial Artificial Chromosome (BAC) Modification: Transformation of the BAC Host with the RecA Vector.
.
Cold Spring Harb Protoc. 2020(7):098129.
Petsko GA
. 2013.
Open questions: Zombie projects, translational research, and the real secret of the inside of the cell.
.
BMC Biol. 11:97.
Kim J
,
Castellano JM
,
Jiang H
,
Basak JM
,
Parsadanian M
,
Pham V
,
Mason SM
,
Paul SM
,
Holtzman DM
. 2009.
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
.
Neuron. 64(5):632-44.
X Yang W
,
Gong S
. 2005.
An overview on the generation of BAC transgenic mice for neuroscience research.
.
Curr Protoc Neurosci. Chapter 5:Unit5.20.
Zhou W
,
Zhu M
,
Wilson MA
,
Petsko GA
,
Fink AL
. 2006.
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
.
J Mol Biol. 356(4):1036-48.
Canet-Avilés RM
,
Wilson MA
,
Miller DW
,
Ahmad R
,
McLendon C
,
Bandyopadhyay S
,
Baptista MJ
,
Ringe D
,
Petsko GA
,
Cookson MR
. 2004.
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
.
Proc Natl Acad Sci U S A. 101(24):9103-8.
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron.
Gu X
,
Li C
,
Wei W
,
Lo V
,
Gong S
,
Li S-H
,
Iwasato T
,
Itohara S
,
Li X-J
,
Mody I
et al.
. 2005.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
.
Neuron. 46(3):433-44.
Gan L
,
Mucke L
. 2008.
Paths of convergence: sirtuins in aging and neurodegeneration.
.
Neuron. 58(1):10-4.
Xie L
,
Xie L
. 2019.
Pathway-Centric Structure-Based Multi-Target Compound Screening for Anti-Virulence Drug Repurposing.
.
Int J Mol Sci. 20(14)
Luo W-jie
,
Wang H
,
Li H
,
Kim BS
,
Shah S
,
Lee H-J
,
Thinakaran G
,
Kim T-W
,
Yu G
,
Xu H
. 2003.
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.
.
J Biol Chem. 278(10):7850-4.
Luo W
,
Ip FCF
,
Fu G
,
Cheung K
,
Tian Y
,
Hu Y
,
Sinha A
,
Cheng EYL
,
Wu X
,
Bustos V
et al.
. 2020.
A Pentacyclic Triterpene from Targets γ-Secretase.
.
ACS Chem Neurosci. 11(18):2827-2835.
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Dodart JC
,
Paul SM
,
Holtzman DM
. 2001.
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 98(15):8850-5.
Mecozzi VJ
,
Berman DE
,
Simoes S
,
Vetanovetz C
,
Awal MR
,
Patel VM
,
Schneider RT
,
Petsko GA
,
Ringe D
,
Small SA
. 2014.
Pharmacological chaperones stabilize retromer to limit APP processing.
.
Nat Chem Biol. 10(6):443-9.
Liu CFeng
,
Liu D
,
Momb J
,
Thomas PW
,
Lajoie A
,
Petsko GA
,
Fast W
,
Ringe D
. 2013.
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.
.
Biochemistry. 52(9):1603-10.
Sanchez-Mejia RO
,
Newman JW
,
Toh S
,
Yu G-Q
,
Zhou Y
,
Halabisky B
,
Cissé M
,
Scearce-Levie K
,
Cheng IH
,
Gan L
et al.
. 2008.
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.
.
Nat Neurosci. 11(11):1311-8.
Liu W
,
Acín-Peréz R
,
Geghman KD
,
Manfredi G
,
Lu B
,
Li C
. 2011.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.
.
Proc Natl Acad Sci U S A. 108(31):12920-4.
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