Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 37 results
Author Title Type [ Year(Desc)]
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2000
Guo M, Gong S, Maric S, Misulovin Z, Pack M, Mahnke K, Nussenzweig MC, Steinman RM.  2000.  A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.. Hum Immunol. 61(8):729-38.
2003
Saura J, Petegnief V, Wu X, Liang Y, Paul SM.  2003.  Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide.. J Neurochem. 85(6):1455-67.
2004
Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H et al..  2004.  Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes.. J Cell Biol. 164(6):923-33.
2005
Gong S, X Yang W.  2005.  Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice.. Curr Protoc Neurosci. Chapter 5:Unit5.21.
Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR.  2005.  Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.. Proc Natl Acad Sci U S A. 102(16):5703-8.
2006
Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XWilliam, Heintz N, Lin S.  2006.  Modified bacterial artificial chromosomes for zebrafish transgenesis.. Methods. 39(3):183-8.
Mattos C, Bellamacina CR, Peisach E, Pereira A, Vitkup D, Petsko GA, Ringe D.  2006.  Multiple solvent crystal structures: probing binding sites, plasticity and hydration.. J Mol Biol. 357(5):1471-82.
2008
Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN.  2008.  Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.. Autism Res. 1(3):147-58.
2009
Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, DeLong C, Hale J, Liu F, Hunter JM, Paul SM.  2009.  Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.. J Neurosci. 29(11):3603-12.
Li Y, Liu W, Oo TF, Wang L, Tang Y, Jackson-Lewis V, Zhou C, Geghman K, Bogdanov M, Przedborski S et al..  2009.  Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.. Nat Neurosci. 12(7):826-8.
2011
Sun B, Gan L.  2011.  Manipulation of gene expression in the central nervous system with lentiviral vectors.. Methods Mol Biol. 670:155-68.
2012
Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN.  2012.  Mass spectrometry tools for analysis of intermolecular interactions.. Methods Mol Biol. 896:387-98.
Syed I, Rathod J, Parmar M, Corcoran GB, Ray SD.  2012.  Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury.. Mol Cell Biochem. 365(1-2):351-61.
Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD.  2012.  Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.. J Biol Chem. 287(32):27255-64.
2013
Paul SM, Doherty JJ, Robichaud AJ, Belfort GM, Chow BY, Hammond RS, Crawford DC, Linsenbardt AJ, Shu H-J, Izumi Y et al..  2013.  The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.. J Neurosci. 33(44):17290-300.
2014
Choi DW, Armitage R, Brady LS, Coetzee T, Fisher W, Hyman S, Pande A, Paul S, Potter W, Roin B et al..  2014.  Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs.. Neuron. 84(3):554-63.
Acuna C, Guo Q, Burré J, Sharma M, Sun J, Südhof TC.  2014.  Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.. Neuron. 82(5):1088-100.
2015
Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul SM.  2015.  Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.. Sci Rep. 5:11161.
2016
Bose A, M Beal F.  2016.  Mitochondrial dysfunction in Parkinson's disease.. J Neurochem.
2017
Krabbe G, S Minami S, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC et al..  2017.  Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.
Pineda A, Burré J.  2017.  Modulating membrane binding of α-synuclein as a therapeutic strategy.. Proc Natl Acad Sci U S A. 114(6):1223-1225.
2018
Guiberson NGuy Lewis, Pineda A, Abramov D, Kharel P, Carnazza KE, Wragg RT, Dittman JS, Burré J.  2018.  Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.. Nat Commun. 9(1):3986.
Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT et al..  2018.  Military-related risk factors for dementia.. Alzheimers Dement. 14(12):1651-1662.
2019
Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M et al..  2019.  Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.. Nat Genet. 51(8):1252-1262.
Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC et al..  2019.  Microglial microRNAs mediate sex-specific responses to tau pathology.. Nat Neurosci.