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Journal Article
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Shi Y
,
Yamada K
,
Liddelow SAntony
,
Smith ST
,
Zhao L
,
Luo W
,
Tsai RM
,
Spina S
,
Grinberg LT
,
Rojas JC
et al.
. 2017.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
.
Nature. 549(7673):523-527.
Cao J
,
Gaamouch FEl
,
Meabon JS
,
Meeker KD
,
Zhu L
,
Zhong MB
,
Bendik J
,
Elder G
,
Jing P
,
Xia J
et al.
. 2017.
ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.
.
Sci Rep. 7(1):11372.
Auclair JR
,
Salisbury JP
,
Johnson JL
,
Petsko GA
,
Ringe D
,
Bosco DA
,
Agar NYR
,
Santagata S
,
Durham HD
,
Agar JN
. 2014.
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
.
Proteomics. 14(10):1152-7.
Barnett D
,
Bohmbach K
,
Grelot V
,
Charlet A
,
Dallérac G
,
Ju YHa
,
Nagai J
,
Orr AG
. 2023.
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting.
.
J Neurosci. 43(45):7463-7471.
Licht-Murava A
,
Meadows SM
,
Palaguachi F
,
Song SC
,
Jackvony S
,
Bram Y
,
Zhou C
,
Schwartz RE
,
Froemke RC
,
Orr AL
et al.
. 2023.
Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
.
Sci Adv. 9(16):eade1282.
Mukherjee K
,
Sharma M
,
Urlaub H
,
Bourenkov GP
,
Jahn R
,
Südhof TC
,
Wahl MC
. 2008.
CASK Functions as a Mg2+-independent neurexin kinase.
.
Cell. 133(2):328-39.
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
Head K
,
Gong S
,
Joseph S
,
Wang C
,
Burkhardt T
,
Rossi MR
,
LaDuca J
,
Matsui S-I
,
Vaughan M
,
Hicks DG
et al.
. 2007.
Defining the expression pattern of the LGI1 gene in BAC transgenic mice.
.
Mamm Genome. 18(5):328-37.
Wahrle SE
,
Jiang H
,
Parsadanian M
,
Hartman RE
,
Bales KR
,
Paul SM
,
Holtzman DM
. 2005.
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
.
J Biol Chem. 280(52):43236-42.
Landon MR
,
Lieberman RL
,
Hoang QQ
,
Ju S
,
Caaveiro JMM
,
Orwig SD
,
Kozakov D
,
Brenke R
,
Chuang G-Y
,
Beglov D
et al.
. 2009.
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.
.
J Comput Aided Mol Des. 23(8):491-500.
Inda MCarmen
,
Joshi S
,
Wang T
,
Bolaender A
,
Gandu S
,
Iii JKoren
,
Che AYue
,
Taldone T
,
Yan P
,
Sun W
et al.
. 2020.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
.
Nat Commun. 11(1):319.
Mukherjee K
,
Sharma M
,
Jahn R
,
Wahl MC
,
Südhof TC
. 2010.
Evolution of CASK into a Mg2+-sensitive kinase.
.
Sci Signal. 3(119):ra33.
Joiner WJ
,
Tang MD
,
Wang LY
,
Dworetzky SI
,
Boissard CG
,
Gan L
,
Gribkoff VK
,
Kaczmarek LK
. 1998.
Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.
.
Nat Neurosci. 1(6):462-9.
Yang X
,
Wen J
,
Yang H
,
Jones IR
,
Zhu X
,
Liu W
,
Li B
,
Clelland CD
,
Luo W
,
Wong MYing
et al.
. 2023.
Functional characterization of Alzheimer's disease genetic variants in microglia.
.
Nat Genet. 55(10):1735-1744.
Yang X
,
Wen J
,
Yang H
,
Jones IR
,
Zhu X
,
Liu W
,
Li B
,
Clelland CD
,
Luo W
,
Wong MYing
et al.
. 2023.
Functional characterization of Alzheimer's disease genetic variants in microglia.
.
Nat Genet. 55(10):1735-1744.
Li L
,
Rutlin M
,
Abraira VE
,
Cassidy C
,
Kus L
,
Gong S
,
Jankowski MP
,
Luo W
,
Heintz N
,
H Koerber R
et al.
. 2011.
The functional organization of cutaneous low-threshold mechanosensory neurons.
.
Cell. 147(7):1615-27.
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Castellano JM
,
Kim J
,
Stewart FR
,
Jiang H
,
DeMattos RB
,
Patterson BW
,
Fagan AM
,
Morris JC
,
Mawuenyega KG
,
Cruchaga C
et al.
. 2011.
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
.
Sci Transl Med. 3(89):89ra57.
Sang T-K
,
Li C
,
Liu W
,
Rodriguez A
,
Abrams JM
,
S Zipursky L
,
Jackson GR
. 2005.
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.
.
Hum Mol Genet. 14(3):357-72.
Bales KR
,
Verina T
,
Dodel RC
,
Du Y
,
Altstiel L
,
Bender M
,
Hyslop P
,
Johnstone EM
,
Little SP
,
Cummins DJ
et al.
. 1997.
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
.
Nat Genet. 17(3):263-4.
Bharadwaj PR
,
Verdile G
,
Barr RK
,
Gupta V
,
Steele JW
,
M Lachenmayer L
,
Yue Z
,
Ehrlich ME
,
Petsko G
,
Ju S
et al.
. 2012.
Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
.
J Alzheimers Dis. 32(4):949-67.
Steele JW
,
Lachenmayer ML
,
Ju S
,
Stock A
,
Liken J
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
.
Mol Psychiatry. 18(8):889-97.
Steele JW
,
Ju S
,
Lachenmayer ML
,
Liken J
,
Stock A
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
.
Mol Psychiatry. 18(8):882-8.
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