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Mapping Dementia-Linked Protein Interactions Yields Potential New Treatment Targets

We’re excited to share our latest research out in CellPress NOW! Using APEX and AP-MS proteomics, we mapped Tau interactomes that were modified by neuronal activity and FTD mutations in hiPSC-derived neurons. Read the press release here. The full article is open access and can be read...

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Targeting the Brain’s Immune Cells May Help Prevent or Treat Alzheimer’s Disease

Our recent study in Science Translational Medicine identifies a TREM2 R47H-specific microglial subpopulation in human AD brain and tauopathy mice, reminiscent of DAM and AKT hyperactivation which can be rescued by pharmacological AKT inhibition. Read the full article here.

Appel Symposium 2021

The Ninth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Tuesday, November 9th, 2021

The Ninth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Tuesday, November 9th, 2021 from 2:30PM - 4:00PM.

This is an outstanding annual event hosted by Dean Choi, Appel Alzheimer's Institute and the Feil Family BMRI. Dr. Li Gan, Director of the Appel Institute will open the symposium, followed by four cutting edge scientific presentations by Dr. Jacqueline Burré from Weill Cornell Medicine, Dr. Ana Maria Cuervo from Albert Einstein College of...

Manu Sharma

Dr. Manu Sharma: Winner of the 2020 Outstanding Teaching and Mentoring Award in Neuroscience!

Dr. Manu Sharma is the winner of the 2020 Feil Family BMRI Mentor of the Year Award in Neuroscience. The award was determined through student nomination and committee review. Congratulations!

Anna Orr

Dr. Anna Orr: Winner of the 2021 Outstanding Teaching and Mentoring Award in Neuroscience!

Anna Orr received the 2021 Outstanding Teaching and Mentoring Award in Neuroscience from the Weill Cornell Graduate School. The award recognizes faculty dedication to training early-stage graduate students in the program.

Weill Cornell Medicine Helen & Robert Appel Alzheimer’s Disease Research Institute 413 E. 69th St. New York, NY 10021