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Found 330 results
Author
Title
Type
[
Year
]
2006
Bales KR
,
Tzavara ET
,
Wu S
,
Wade MR
,
Bymaster FP
,
Paul SM
,
Nomikos GG
. 2006.
Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.
.
J Clin Invest. 116(3):825-32.
Yang Z
,
Jiang H
,
Chaichanasakul T
,
Chachainasakul T
,
Gong S
,
Yang XWilliam
,
Heintz N
,
Lin S
. 2006.
Modified bacterial artificial chromosomes for zebrafish transgenesis.
.
Methods. 39(3):183-8.
Mattos C
,
Bellamacina CR
,
Peisach E
,
Pereira A
,
Vitkup D
,
Petsko GA
,
Ringe D
. 2006.
Multiple solvent crystal structures: probing binding sites, plasticity and hydration.
.
J Mol Biol. 357(5):1471-82.
Zhou W
,
Zhu M
,
Wilson MA
,
Petsko GA
,
Fink AL
. 2006.
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
.
J Mol Biol. 356(4):1036-48.
Das C
,
Hoang QQ
,
Kreinbring CA
,
Luchansky SJ
,
Meray RK
,
Ray SS
,
Lansbury PT
,
Ringe D
,
Petsko GA
. 2006.
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.
.
Proc Natl Acad Sci U S A. 103(12):4675-80.
Burré J
,
Beckhaus T
,
Corvey C
,
Karas M
,
Zimmermann H
,
Volknandt W
. 2006.
Synaptic vesicle proteins under conditions of rest and activation: analysis by 2-D difference gel electrophoresis.
.
Electrophoresis. 27(17):3488-96.
2005
Nicole O
,
Goldshmidt A
,
Hamill CE
,
Sorensen SD
,
Sastre A
,
Lyuboslavsky P
,
Hepler JR
,
McKeon RJ
,
Traynelis SF
. 2005.
Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.
.
J Neurosci. 25(17):4319-29.
Brendza RP
,
Bacskai BJ
,
Cirrito JR
,
Simmons KA
,
Skoch JM
,
Klunk WE
,
Mathis CA
,
Bales KR
,
Paul SM
,
Hyman BT
et al.
. 2005.
Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.
.
J Clin Invest. 115(2):428-33.
Wahrle SE
,
Jiang H
,
Parsadanian M
,
Hartman RE
,
Bales KR
,
Paul SM
,
Holtzman DM
. 2005.
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
.
J Biol Chem. 280(52):43236-42.
Du K
,
Sharma M
,
Lukacs GL
. 2005.
The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.
.
Nat Struct Mol Biol. 12(1):17-25.
Dodart J-C
,
Marr RA
,
Koistinaho M
,
Gregersen BM
,
Malkani S
,
Verma IM
,
Paul SM
. 2005.
Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 102(4):1211-6.
Morciano M
,
Burré J
,
Corvey C
,
Karas M
,
Zimmermann H
,
Volknandt W
. 2005.
Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis.
.
J Neurochem. 95(6):1732-45.
Sang T-K
,
Li C
,
Liu W
,
Rodriguez A
,
Abrams JM
,
S Zipursky L
,
Jackson GR
. 2005.
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.
.
Hum Mol Genet. 14(3):357-72.
Gong S
,
X Yang W
. 2005.
Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice.
.
Curr Protoc Neurosci. Chapter 5:Unit5.21.
Beilina A
,
Van Der Brug M
,
Ahmad R
,
Kesavapany S
,
Miller DW
,
Petsko GA
,
Cookson MR
. 2005.
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.
.
Proc Natl Acad Sci U S A. 102(16):5703-8.
Andersen OM
,
Reiche J
,
Schmidt V
,
Gotthardt M
,
Spoelgen R
,
Behlke J
,
von Arnim CAF
,
Breiderhoff T
,
Jansen P
,
Wu X
et al.
. 2005.
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
.
Proc Natl Acad Sci U S A. 102(38):13461-6.
X Yang W
,
Gong S
. 2005.
An overview on the generation of BAC transgenic mice for neuroscience research.
.
Curr Protoc Neurosci. Chapter 5:Unit5.20.
Gu X
,
Li C
,
Wei W
,
Lo V
,
Gong S
,
Li S-H
,
Iwasato T
,
Itohara S
,
Li X-J
,
Mody I
et al.
. 2005.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
.
Neuron. 46(3):433-44.
Kaczmarek LK
,
Bhattacharjee A
,
Desai R
,
Gan L
,
Song P
,
von Hehn CAA
,
Whim MD
,
Yang B
. 2005.
Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.
.
Hear Res. 206(1-2):133-45.
Chen J
,
Zhou Y
,
Mueller-Steiner S
,
Chen L-F
,
Kwon H
,
Yi S
,
Mucke L
,
Gan L
. 2005.
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
.
J Biol Chem. 280(48):40364-74.
Hamill CE
,
Goldshmidt A
,
Nicole O
,
McKeon RJ
,
Brat DJ
,
Traynelis SF
. 2005.
Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.
.
Clin Neurosurg. 52:29-44.
Cirrito JR
,
Yamada KA
,
Finn MBeth
,
Sloviter RS
,
Bales KR
,
May PC
,
Schoepp DD
,
Paul SM
,
Mennerick S
,
Holtzman DM
. 2005.
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.
.
Neuron. 48(6):913-22.
2004
DeMattos RB
,
Cirrito JR
,
Parsadanian M
,
May PC
,
O'dell MA
,
Taylor JW
,
Harmony JAK
,
Aronow BJ
,
Bales KR
,
Paul SM
et al.
. 2004.
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.
.
Neuron. 41(2):193-202.
Koistinaho M
,
Lin S
,
Wu X
,
Esterman M
,
Koger D
,
Hanson J
,
Higgs R
,
Liu F
,
Malkani S
,
Bales KR
et al.
. 2004.
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.
.
Nat Med. 10(7):719-26.
Sparwasser T
,
Gong S
,
Li JYH
,
Eberl G
. 2004.
General method for the modification of different BAC types and the rapid generation of BAC transgenic mice.
.
Genesis. 38(1):39-50.
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