Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 28 results
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A
Abramov D, Guiberson NGuy Lewis, Daab A, Na Y, Petsko GA, Sharma M, Burré J.  2020.  Targeted stabilization of Munc18-1 function via pharmacological chaperones.. EMBO Mol Med. :e12354.
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de Haas R, Heltzel LCMW, Tax D, van den Broek P, Steenbreker H, Verheij MMM, Russel FGM, Orr AL, Nakamura K, Smeitink JAM.  2019.  To be or not to be pink(1): contradictory findings in an animal model for Parkinson's disease.. Brain Commun. 1(1):fcz016.
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Evering TH, Marston JL, Gan L, Nixon DF.  2023.  Transposable elements and Alzheimer's disease pathogenesis.. Trends Neurosci. 46(3):170-172.
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Fernandopulle MS, Prestil R, Grunseich C, Wang C, Gan L, Ward ME.  2018.  Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.. Curr Protoc Cell Biol. 79(1):e51.
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Gan L.  2007.  Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease.. Drug News Perspect. 20(4):233-9.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
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Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, D Surmeier J et al..  2008.  A translational profiling approach for the molecular characterization of CNS cell types.. Cell. 135(4):738-48.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of the A Homology Arm (A-Box) and B Homology Arm (B-Box).. Cold Spring Harb Protoc. 2020(4):098046.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Cloning of the A and B Homology Arms into the Shuttle Vector.. Cold Spring Harb Protoc. 2020(4):098053.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Verification of Co-Integrates and Selection of Resolved BAC Clones.. Cold Spring Harb Protoc. 2020(4):098087.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Electroporation of Competent BAC Host Cells with the Recombinant Shuttle Vector.. Cold Spring Harb Protoc. 2020(4):098079.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation and Verification of the Recombinant Shuttle Vector.. Cold Spring Harb Protoc. 2020(4):098061.
Heintz N, Gong S.  2020.  Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of Shuttle Vector DNA.. Cold Spring Harb Protoc. 2020(4):098038.
Heymont J, Berenfeld L, Collins J, Kaganovich A, Maynes B, Moulin A, Ratskovskaya I, Poon PP, Johnston GC, Kamenetsky M et al..  2000.  TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation.. Proc Natl Acad Sci U S A. 97(23):12672-7.
Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S.  2014.  Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.. Mol Neurodegener. 9:52.
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Kim KHye, Liu J, Galvin RJSells, Dage JL, Egeland JA, Smith RC, Merchant KM, Paul SM.  2015.  Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.. PLoS One. 10(11):e0142693.
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Muchardt C, Seeler JS, Nirula A, Gong S, Gaynor R.  1992.  Transcription factor AP-2 activates gene expression of HTLV-I.. EMBO J. 11(7):2573-81.
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Pappas DJ, Gabatto PA, Oksenberg D, Khankhanian P, Baranzini SE, Gan L, Oksenberg JR.  2012.  Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules.. Neuroscience. 226:10-20.
Paul SM.  2011.  Therapeutic antibodies for brain disorders.. Sci Transl Med. 3(84):84ps20.
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Rho J, Gong S, Kim N, Choi Y.  2001.  TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo.. Mol Cell Biol. 21(24):8365-70.
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Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Huttenhain R, Kauwe G et al..  2022.  Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.. Cell. 185(4):712-728.e14.
Tracy TE, Gan L.  2018.  Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease.. Curr Opin Neurobiol. 51:134-138.
U
Udeochu J, Sayed FA, Gan L.  2018.  TREM2 and Amyloid Beta: A Love-Hate Relationship.. Neuron. 97(5):991-993.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERuth S, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G et al..  2023.  Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.. Nat Neurosci. 26(5):737-750.
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Wallace CH, Oliveros G, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira M.  2022.  Timapiprant, a prostaglandin D2 receptor antagonist, ameliorates pathology in a rat Alzheimer's model.. Life Sci Alliance. 5(12)