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Found 325 results
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2016
Wes PD
,
Sayed FA
,
Bard F
,
Gan L
. 2016.
Targeting microglia for the treatment of Alzheimer's Disease.
.
Glia. 64(10):1710-32.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 92(1):252-264.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 90(4):724-39.
Bettayeb K
,
Chang JC
,
Luo W
,
Aryal S
,
Varotsis D
,
Randolph L
,
Netzer WJ
,
Greengard P
,
Flajolet M
. 2016.
δ-COP modulates Aβ peptide formation via retrograde trafficking of APP.
.
Proc Natl Acad Sci U S A. 113(19):5412-7.
2015
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
Kember RL
,
Georgi B
,
Bailey-Wilson JE
,
Stambolian D
,
Paul SM
,
Bućan M
. 2015.
Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder.
.
BMC Genet. 16:27.
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
Burré J
,
Sharma M
,
Südhof TC
. 2015.
Definition of a molecular pathway mediating α-synuclein neurotoxicity.
.
J Neurosci. 35(13):5221-32.
Luo W
,
Liu W
,
Hu X
,
Hanna M
,
Caravaca A
,
Paul SM
. 2015.
Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.
.
Sci Rep. 5:11161.
S Minami S
,
Shen V
,
Le D
,
Krabbe G
,
Asgarov R
,
Perez-Celajes L
,
Lee C-H
,
Li J
,
Donnelly-Roberts D
,
Gan L
. 2015.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
.
Biochem Pharmacol. 97(4):454-462.
Cho S-H
,
Chen JA
,
Sayed F
,
Ward ME
,
Gao F
,
Nguyen TA
,
Krabbe G
,
Sohn PDongmin
,
Lo I
,
Minami S
et al.
. 2015.
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.
.
J Neurosci. 35(2):807-18.
Orr AL
,
Vargas L
,
Turk CN
,
Baaten JE
,
Matzen JT
,
Dardov VJ
,
Attle SJ
,
Li J
,
Quackenbush DC
,
Goncalves RLS
et al.
. 2015.
Suppressors of superoxide production from mitochondrial complex III.
.
Nat Chem Biol. 11(11):834-6.
Burré J
. 2015.
The Synaptic Function of α-Synuclein.
.
J Parkinsons Dis. 5(4):699-713.
Bacaj T
,
Wu D
,
Burré J
,
Malenka RC
,
Liu X
,
Südhof TC
. 2015.
Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles.
.
PLoS Biol. 13(10):e1002267.
Kim KHye
,
Liu J
,
Galvin RJSells
,
Dage JL
,
Egeland JA
,
Smith RC
,
Merchant KM
,
Paul SM
. 2015.
Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.
.
PLoS One. 10(11):e0142693.
2014
Fargo KN
,
Aisen P
,
Albert M
,
Au R
,
Corrada MM
,
DeKosky S
,
Drachman D
,
Fillit H
,
Gitlin L
,
Haas M
et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Auclair JR
,
Salisbury JP
,
Johnson JL
,
Petsko GA
,
Ringe D
,
Bosco DA
,
Agar NYR
,
Santagata S
,
Durham HD
,
Agar JN
. 2014.
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
.
Proteomics. 14(10):1152-7.
McKnight NC
,
Zhong Y
,
Wold MS
,
Gong S
,
Phillips GR
,
Dou Z
,
Zhao Y
,
Heintz N
,
Zong W-X
,
Yue Z
. 2014.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
.
PLoS Genet. 10(10):e1004626.
Linsenbardt AJ
,
Taylor A
,
Emnett CM
,
Doherty JJ
,
Krishnan K
,
Covey DF
,
Paul SM
,
Zorumski CF
,
Mennerick S
. 2014.
Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.
.
Neuropharmacology. 85:232-42.
Ward ME
,
Taubes A
,
Chen R
,
Miller BL
,
Sephton CF
,
Gelfand JM
,
Minami S
,
Boscardin J
,
Martens LHerl
,
Seeley WW
et al.
. 2014.
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
.
J Exp Med. 211(10):1937-45.
Georgi B
,
Craig D
,
Kember RL
,
Liu W
,
Lindquist I
,
Nasser S
,
Brown C
,
Egeland JA
,
Paul SM
,
Bućan M
. 2014.
Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.
.
PLoS Genet. 10(3):e1004229.
Choi DW
,
Armitage R
,
Brady LS
,
Coetzee T
,
Fisher W
,
Hyman S
,
Pande A
,
Paul S
,
Potter W
,
Roin B
et al.
. 2014.
Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs.
.
Neuron. 84(3):554-63.
Acuna C
,
Guo Q
,
Burré J
,
Sharma M
,
Sun J
,
Südhof TC
. 2014.
Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.
.
Neuron. 82(5):1088-100.
Orr AL
,
Ashok D
,
Sarantos MR
,
Ng R
,
Shi T
,
Gerencser AA
,
Hughes RE
,
Brand MD
. 2014.
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.
.
PLoS One. 9(2):e89938.
Mecozzi VJ
,
Berman DE
,
Simoes S
,
Vetanovetz C
,
Awal MR
,
Patel VM
,
Schneider RT
,
Petsko GA
,
Ringe D
,
Small SA
. 2014.
Pharmacological chaperones stabilize retromer to limit APP processing.
.
Nat Chem Biol. 10(6):443-9.
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