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Found 325 results
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2012
S Minami S
,
Sun B
,
Popat K
,
Kauppinen T
,
Pleiss M
,
Zhou Y
,
Ward ME
,
Floreancig P
,
Mucke L
,
Desai T
et al.
. 2012.
Selective targeting of microglia by quantum dots.
.
J Neuroinflammation. 9:22.
Burré J
,
Sharma M
,
Südhof TC
. 2012.
Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.
.
J Neurosci. 32(43):15227-42.
Pappas DJ
,
Gabatto PA
,
Oksenberg D
,
Khankhanian P
,
Baranzini SE
,
Gan L
,
Oksenberg JR
. 2012.
Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules.
.
Neuroscience. 226:10-20.
2011
Etherton MR
,
Tabuchi K
,
Sharma M
,
Ko J
,
Südhof TC
. 2011.
An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
.
EMBO J. 30(14):2908-19.
Sharma M
,
Burré J
,
Südhof TC
. 2011.
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.
.
Nat Cell Biol. 13(1):30-9.
Cho S-H
,
Sun B
,
Zhou Y
,
Kauppinen TM
,
Halabisky B
,
Wes P
,
Ransohoff RM
,
Gan L
. 2011.
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.
.
J Biol Chem. 286(37):32713-22.
Li L
,
Rutlin M
,
Abraira VE
,
Cassidy C
,
Kus L
,
Gong S
,
Jankowski MP
,
Luo W
,
Heintz N
,
H Koerber R
et al.
. 2011.
The functional organization of cutaneous low-threshold mechanosensory neurons.
.
Cell. 147(7):1615-27.
Castellano JM
,
Kim J
,
Stewart FR
,
Jiang H
,
DeMattos RB
,
Patterson BW
,
Fagan AM
,
Morris JC
,
Mawuenyega KG
,
Cruchaga C
et al.
. 2011.
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
.
Sci Transl Med. 3(89):89ra57.
Sun B
,
Gan L
. 2011.
Manipulation of gene expression in the central nervous system with lentiviral vectors.
.
Methods Mol Biol. 670:155-68.
Liu W
,
Acín-Peréz R
,
Geghman KD
,
Manfredi G
,
Lu B
,
Li C
. 2011.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.
.
Proc Natl Acad Sci U S A. 108(31):12920-4.
Kauppinen TM
,
Suh SWon
,
Higashi Y
,
Berman AE
,
Escartin C
,
Won SJoon
,
Wang C
,
Cho S-H
,
Gan L
,
Swanson RA
. 2011.
Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.
.
J Neuroinflammation. 8:152.
Zhang F
,
Wang S
,
Gan L
,
Vosler PS
,
Gao Y
,
Zigmond MJ
,
Chen J
. 2011.
Protective effects and mechanisms of sirtuins in the nervous system.
.
Prog Neurobiol. 95(3):373-95.
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
Witten IB
,
Steinberg EE
,
Lee SYeun
,
Davidson TJ
,
Zalocusky KA
,
Brodsky M
,
Yizhar O
,
Cho SL
,
Gong S
,
Ramakrishnan C
et al.
. 2011.
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.
.
Neuron. 72(5):721-33.
Birket MJ
,
Orr AL
,
Gerencser AA
,
Madden DT
,
Vitelli C
,
Swistowski A
,
Brand MD
,
Zeng X
. 2011.
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.
.
J Cell Sci. 124(Pt 3):348-58.
Cissé M
,
Halabisky B
,
Harris J
,
Devidze N
,
Dubal DB
,
Sun B
,
Orr A
,
Lotz G
,
Kim DH
,
Hamto P
et al.
. 2011.
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.
.
Nature. 469(7328):47-52.
Paul SM
. 2011.
Therapeutic antibodies for brain disorders.
.
Sci Transl Med. 3(84):84ps20.
Ju S
,
Tardiff DF
,
Han H
,
Divya K
,
Zhong Q
,
Maquat LE
,
Bosco DA
,
Hayward LJ
,
Brown RH
,
Lindquist S
et al.
. 2011.
A yeast model of FUS/TLS-dependent cytotoxicity.
.
PLoS Biol. 9(4):e1001052.
2010
Min S-W
,
Cho S-H
,
Zhou Y
,
Schroeder S
,
Haroutunian V
,
Seeley WW
,
Huang EJ
,
Shen Y
,
Masliah E
,
Mukherjee C
et al.
. 2010.
Acetylation of tau inhibits its degradation and contributes to tauopathy.
.
Neuron. 67(6):953-66.
Burré J
,
Sharma M
,
Tsetsenis T
,
Buchman V
,
Etherton MR
,
Südhof TC
. 2010.
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
.
Science. 329(5999):1663-7.
Hurtado DE
,
Molina-Porcel L
,
Iba M
,
Aboagye AK
,
Paul SM
,
Trojanowski JQ
,
Lee VM-Y
. 2010.
A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.
.
Am J Pathol. 177(4):1977-88.
Mukherjee K
,
Sharma M
,
Jahn R
,
Wahl MC
,
Südhof TC
. 2010.
Evolution of CASK into a Mg2+-sensitive kinase.
.
Sci Signal. 3(119):ra33.
He G
,
Luo W
,
Li P
,
Remmers C
,
Netzer WJ
,
Hendrick J
,
Bettayeb K
,
Flajolet M
,
Gorelick F
,
Wennogle LP
et al.
. 2010.
Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
.
Nature. 467(7311):95-8.
Paul SM
,
Mytelka DS
,
Dunwiddie CT
,
Persinger CC
,
Munos BH
,
Lindborg SR
,
Schacht AL
. 2010.
How to improve R&D productivity: the pharmaceutical industry's grand challenge.
.
Nat Rev Drug Discov. 9(3):203-14.
Li X-J
,
Orr AL
,
Li S
. 2010.
Impaired mitochondrial trafficking in Huntington's disease.
.
Biochim Biophys Acta. 1802(1):62-5.
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